OsteoDx is a pioneering company dedicated to transforming how bone health is assessed. Our mission is to provide smarter, more precise tools for evaluating skeletal health, moving beyond traditional bone mineral density (BMD) measurements to direct, functional assessments of bone properties.
At the forefront of this innovation is Cortical Bone Mechanics Technology™ (CBMT™), a novel, noninvasive device that measures bending stiffness and calculates flexural rigidity—mechanical properties that determine whole-bone strength and fracture resistance.
Current bone health assessments measure bone density but do not directly assess whole-bone strength—an integral factor in fracture resistance. OsteoDx changes that.
OsteoDx’s device applies controlled multi-frequency vibration at multiple forearm sites to conduct dynamic mechanical testing of the ulna—a bone well-suited for cortical bone assessment due to its structural properties and loading conditions. Utilizing proprietary Cortical Bone Mechanics Technology™ (CBMT™), the system analyzes frequency response functions to quantify bending stiffness and calculate flexural rigidity, fundamental mechanical properties directly related to whole-bone strength.
What we did: Jeff Spitzner was the business founder of OsteoDx (formerly, AEIOU Scientific) and its CEO from inception through its successful investment fundraising launch and product readiness for scientific sales. The Company was able to prove its scientific instrument in per reviewed publications and achieve FDA Pre-Submission review with only non-dilutive capital. The mission of AEIOU is to improve the targeting of medical care for the prevention of low-trauma fractures. OsteoDx is developing and commercializing Ohio University’s patented Cortical Bone Mechanics Technology™ (CBMT) – first as a scientific laboratory instrument, and then later as a non-invasive medical device to be approved by FDA for improving the diagnosis and monitoring of osteoporosis and other bone diseases. The tech has been tested extensively and uniquely provides accurate information about the total strength of bone in vivo.